“Do you want to know how great God truly is? If so, then you will have to discover how insignificant you truly are, and this means you will have to be brought low, perhaps to the deepest reaches of depression. But it will be worth it, and it will make you more useful to God as well, just as it did Job. Notice, for example, that at the beginning of the book we are told that Job offered sacrifices for his children and interceded for them (1:5). But at the end of the book Job’s ministry was expanded to include his friends (42:7-9). Thus he found that he was able to minister to the very friends who had let him down, and he was able to do so in a way he never could have had he not gone through the trials he went through. We are also told that Job received more blessing from the Lord than ever, after he had gone through all of his trials (42:12a).”
From a series at Reformed Baptist Blog on Depression.